Prozac

Believe it or not, Gettysburg College researcher Peter Fong decided to dope up his subjects, fingernail clams, by putting them on antidepressants. And while the phrase "happy as a clam" didn't exactly originate with Fong's research, his unique Prozac prescription kick-started their social lives.

Prozac decreases the uptake of serotonin, making more of the neurosecretion available to the nervous system. In the bivalves' case, this led to an overwhelming urge for synchronous spawning, a boon both for clam farmers and gawky teenage clams alike.